Etabus 250mg 36 tabs
DOSAGE AND ADMINISTRATION: Oral .
Initial , maximum 500 mg per day for a week or two doses . The maintenance dose is 250 mg daily .
Some patients may experience mild sedation with the product, so their intake is recommended before bedtime.
Store at room temperature to no more than 30 ° C and dry temperature.
Contraindications ETABUS should not be administered to patients who are being treated or have been in recent treatment of metronidazole , paraldehyde , alcohol or prescriptions containing alcohol as cough syrups , tonics and the like.
ETABUS is contraindicated in patients with myocardial disease or coronary occlusion, psychoses , and hypersensitivity to disulfiram or other thiuram derivatives , such as compounds used in pesticides and rubber vulcanization .
ADVERSE REACTIONS : After applying ETABUS may occur optic neuritis , peripheral neuritis , polyneuritis and peripheral neuropathy.
RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION : The safety of ETABUS during pregnancy or lactation has not been determined.
ETABUS produces a highly unpleasant reaction in the patient treated , ingesting even small amounts of this alcohol. ETABUS blocks the oxidation of alcohol in step acetaldehyde .
During the metabolism of alcohol consumed after ETABUS administration , the blood acetaldehyde concentrations may become 5 to 10 times higher than in the normal metabolism of the same amount of alcohol.
The accumulation of acetaldehyde produces a number of unpleasant symptoms that we refer to as the alcohol reaction ETABUS hereafter . This reaction, which is proportional to the dose of both ( ETABUS and alcohol) , persist while being metabolized ingested alcohol.
ETABUS not change the time of removal of alcohol. ETABUS slowly absorbed through the digestive tract wall and is removed slowly from the bloodstream.
The ETABUS alcohol reaction can occur again and up to two weeks after discontinuing administration ETABUS .
Recurrent and prolonged administration of ETABUS not produce tolerance , on the contrary , the longer the treatment lasts, the more sensitive the patient becomes a present ETABUS alcohol reaction.